THE SMART TRICK OF PKRRATING THAT NOBODY IS DISCUSSING

The activated enzyme then phosphorylates its key substrate, the translational initiation element eIF2α. The resulting translational arrest blocks viral replication. PKR belongs to the conserved family members of 4 protein kinases (PKR, PERK, GCN2, HRI) that every one phosphorylate eIF2α in response to different stimuli12, triggering the integrate